Experimental Stress Dermatitis1

Experimental models of stress

Illustrating the complexity of the stress response and its multifaceted manifestations is the leading idea of this overview of experimental paradigms used for stress induction in laboratory animals. The description of key features of models based on naturalistic stressors, pharmacological challenges, and genomic manipulations is complemented by comprehensive analysis of physiological, behaviora...

Oxidative stress and experimental carcinogenesis.

The focus of this review is to provide state-of-the-art knowledge on the involvement of oxygen free radicals (OFR) in carcinogenesis with a particular reference to skin model system as the process of cancer development is best understood in this organ. However, a brief description of the role of OFR in other organs is also provided. The term OFR refers to forms of oxygen exhibiting high reactiv...

Increased oxidative stress in experimental renovascular hypertension.

The pathophysiological mechanisms responsible for maintenance of chronic renovascular hypertension remain undefined. Excess angiotensin II generation may lead to release of reactive oxygen species and increased vasoconstrictor activity. To examine the potential involvement of oxidation-sensitive mechanisms in the pathophysiology of renovascular hypertension, blood samples were collected and ren...

Manual on Experimental Stress Analysis Fifth Edition

An Experimental Approach for Delayed Stress Corrosion

Failures of structural and mechanical components have long been attributed to environmentally assisted cracking (EAC). The umbrella of EAC encompasses several phenomena, including stress corrosion cracking (SCC), corrosion fatigue (CF), hydrogen embrittlement (HE) and liquid metal embrittlement (LME). The latter, LME, has resulted in the failure of components in petrochemical and aeronautical i...